Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019: the …

SG Deftereos, G Giannopoulos, DA Vrachatis… - JAMA network …, 2020 - jamanetwork.com
Importance Severe acute respiratory syndrome coronavirus 2 infection has evolved into a
global pandemic. Low-dose colchicine combines anti-inflammatory action with a favorable
safety profile. Objective To evaluate the effect of treatment with colchicine on cardiac and
inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus
disease 2019 (COVID-19). Design, Setting, and Participants In this prospective, open-label,
randomized clinical trial (the Greek Study in the Effects of Colchicine in COVID-19 …